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The active ingredient of Motilium is one of the most important means for the treatment of upper abdominal pain, vomiting, nausea and flatulence, where‘s the passage through the stomach, including accelerated. Since the active ingredient can cross not the blood brain barrier, it is very rare side effects in the central nervous system. Learn everything there is to know about Motilium side effects and take advantage of.
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The Messenger communication between nerve cells and neurotransmitters also called mediated, has a variety of tasks in the central nervous system (brain and spinal cord). It acts, inter alia, in which control the movement, contributes to a so-called “happiness hormone” positive feelings caused by excessive psychoses and delusions and affects the levels of prolactin in the blood (prolactin stimulates milk production in the breast women).


The drug acts as an inhibitor (antagonist) of the docking points for dopamine Motilium. It blocks them, cause dopamine can no longer bind to them. Since the active ingredient however the blood brain barrier does not overcome the barrier of protection against potentially harmful substances in the blood can, or no, Motilium effect not on the central nervous system (CNS). This an effect of dopamine in the brain mobility that‘s otherwise suppress would controlled and nearly excluded on the psyche.


A special part of the CNS is the so-called vomiting Center. It is located in the brain stem and in the adjacent elongated spinal cord. Here is the blood brain barrier “riddled” with this part very quickly responds to harmful substances in the blood with nausea and vomiting. This protects the body by more intake of these substances. Since the communication of nerve cells is partially controlled by dopamine in this region, the medicine Motilium can here his job. Block the docking of nausea and vomiting can be reduced


Another positive side effect of taking Motilium, completing it is unclear is accelerating gastric emptying towards the intestine. Thus the stomach is relieved, which can reduce in addition, nausea and bloating.


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After taking Motilium, half an hour to an hour, medicine at the highest level is recorded quickly in the gut into the bloodstream and reached there after. However, it is, to a large extent already in the intestinal mucosa and the liver, so that only about 15 percent of the active ingredient reach and affect the blood circulation. After about seven to nine hours the DMotiliumin is half ausgeschieden-. One-third of urine, two-thirds on the Chair
When do I use Motilium?
The medicine Motilium is approved for the treatment of nausea, vomiting, bloating, and abdominal pain.
Motilium milk production to promote and thereby effectively able to breastfeed a so-called “off-label use”, a usage outside of the approved indications is his. Because DMotiliumin not happen the central nervous system, but also hardly stimulates milk production in the mother‘s milk and effectively and relatively little side effects, is often used for this purpose by mothers with breastfeeding problems.
Since the treatment of symptom-based, Motilium be discontinued if symptoms improve again. The duration of the intake should not exceed four weeks except on special instructions from the doctor.

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